CRYAA protein (30R-1014)

Purified recombinant Human CRYAA protein

Synonyms Alpha-crystallin A chain protein, Crystallin Alpha 1 protein, Acry-1 protein, CRYAA protein, HSPB 4 protein, Crystallin alpha A protein, , HspB4 protein, CRYA 1 protein, Heat shock protein beta 4 protein, Zonular Central Nuclear Cataract protein, Alpha crystallin A chain protein, CRYA1 protein, Heat shock protein beta-4 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CRYAA protein (30R-1014)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 19.9 kDa (173aa)
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 50mM NaCl, 1mM EDTA.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Alpha crystallins are composed of two gene products ; alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.

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Images

  • Coomassie Blue stained SDS-PAGE of CRYAA protein (30R-1014) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €159.94
Size: 100 ug
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