CSTB antibody (10R-1081)

Mouse monoclonal CSTB antibody

Synonyms Monoclonal CSTB antibody, Anti-CSTB antibody, Stefin B antibody, Liver thiol proteinase inhibitor antibody, EPM1 antibody, PME antibody, CSTB antibody, CYTB antibody, CST6 antibody, CystatinB CHROW21 antibody, CPI B antibody, Cystatin B antibody, STFB. antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen CSTB antibody was raised in mouse using recombinant human CSTB (1-98aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 2F1
Isotype IgG2b kappa
Source Anti-human CSTB antibody, clone 2F1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CSTB protein.
Method of Purification CSTB antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to from a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes in cells. CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.

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Availability: In stock

Price: €249.33
Size: 100 ul
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