CTACK protein (Mouse) (30R-AC081)
Purified recombinant Mouse CTACK protein
Overview
Overview
| Synonyms | Cuteaneous T-cell Attracting Chemokine protein, Skinkine protein, ALP protein, CCL27 protein, Eskine protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of CTACK protein corresponding to amino acids LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 10.9 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract CXCR3 transfected HEK/293 cells using a concentration range of 10.0-100.0 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. |
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