CtBP1 protein (30R-1495)

Purified recombinant Human CtBP1 protein

Synonyms CtBP 1, CtBP-1 protein, CtBP-1, CTBP protein, C-terminal-binding protein 1 isoform 1 C terminal binding protein 1 protein, CTBP1 protein, CtBP 1 protein, MGC104684., CtBP1, BARS protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of CtBP1 protein (30R-1495)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-440 amino acids: MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 47.5 kDa (440aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 100mM NaCl and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance C-terminal-binding protein 1 isoform 1, also known as CtBP1, is expressed from embryo to adult. This protein binds to the C-terminus of adenovirus E1A. It is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. Also, CtBP1 associates in complexes with histone deacetylases (HDAC), the G9a histone methyltransferase, and LSD1 histone demethylase illustrating its role in transcriptional repression. Recombinant human CtBP1 was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of CtBP1 protein (30R-1495) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €206.99
Size: 100 ug
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