CtBP2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human CTBP2,identical to the related rat and Rabbit sequences, as the immunogen
Immunocytochemical analysis using CtBP2 antibody (70R-14092)
Immunocytochemistry of Hela cells
CtBP2 antibody
Immunocytochemical analysis using CtBP2 antibody (70R-14092)
Immunocytochemistry of Hela cells
Immunohistochemical staining using CtBP2 antibody (70R-14092)
Immunohistochemistry of paraffin-embedded section of Human Mammary Cancer Tissue
Western Blot analysis using CtBP2 antibody (70R-14092)
Lane 1:Rat Brain Tissue Lysate; Lane 2:Rat Spleen Tissue Lysate; Lane 3:Hela Cell Lysate; Lane 4:293T Cell Lysate; Lane 5:COLO320 Cell Lysate; Lane 6:U87 Cell Lysate; Lane 7:SW620 Cell Lysate
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
CtBP2 antibody was purified by affinity chromatography
Optimal conditions to be determined by the end user
Storage & Safety
Storage
Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.
General Information
Biological Significance
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.