CTCF antibody (10R-2948)

Rat monoclonal CTCF antibody

Synonyms Monoclonal CTCF antibody, Anti-CTCF antibody, 11-Zinc finger protein antibody, CTC F antibody, CCCTC-binding factor antibody, CTC-F antibody, Transcriptional repressor CTCF antibody
Specificity Mouse
Applications IF, WB
Immunogen CTCF antibody was raised in Rat using Mouse CTCF-N-terminal fragment as the immunogen.

Specifications

Host Rat
Clone KT71
Isotype IgG2a
Method of Purification CTCF antibody was purified by Protein G chromatography.
Form & Buffer Supplied in PBS containing 0.1% sodium azide as a preservative
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF: 1-10 ug/ml; WB: 0.1-1 ug/ml

Storage & Safety

Storage Store at 4 deg C for up to 1 month. For long term storage, aliquot and store at -20 to -80 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide which is hazardous

General Information

Biological Significance The protein CTCF plays heavily in the role of repressing the insulin-like growth factor 2 gene, by binding to the H-19 imprinting control region (ICR) along with differentially-methylated region-1 (DMR1) and MAR3. Binding of targeting sequence elements by CTCF can block the interaction between enhancers and promoters, therefore limiting the activity of enhancers to certain functional domains. Besides acting as enhancer blocking, CTCF can also act as a chromatin barrier by preventing the spread of heterochromatin structures.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: €190.59
Size: 100 ug
OR
Shipping
View Our Distributors