CXCR4 antibody (20R-CG008)
Goat polyclonal CXCR4 antibody
Overview
Overview
| Synonyms | Polyclonal CXCR4 antibody, Anti-CXCR4 antibody, CXCR-4 antibody, CXCR4, CXCR 4 antibody, CXCR-4, CXCR 4 |
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| Specificity | Murine |
| Cross Reactivity | Xenopus |
| Applications | ELISA, IHC, WB |
| Immunogen | CXCR4 antibody was raised in goat using YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. as the immunogen. |
Images
Immunohistochemical staining using CXCR4 antibody (20R-CG008)
Immunohistochemistry on paraffin section of mouse spleen
Specifications
| Host | Goat |
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| Form & Buffer | 10mM KHPO4, 140mM NaCl with 1 mg/ml BSA and 0.1 % NaN3. |
| Concentration | Typically 1-5 mg/ml |
Usage & Assay Information
| Usage Recommendations | ELISA: 1:25,000, IHC: 1:150, WB: 1:500 |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C for short term storage, -70 deg C for long-term storage. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
General Information
| Biological Significance | Chemokine receptors are G protein-coupled receptors (GPCRs) and play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. |
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