Cyclin D1 antibody (10R-8605)
Mouse monoclonal Cyclin D1 antibody
Overview
Overview
| Synonyms | Monoclonal Cyclin D1 antibody, Anti-Cyclin D1 antibody, CCND1 antibody, cyclin D1 antibody, B-cell CLL/lymphoma 1 antibody, B-cell lymphoma 1 protein antibody, bcl1 antibody, bcl-1 antibody, BCL-1 oncogene antibody, BOS_25001 antibody, cD1 antibody, cycd1 antibody, cyclin D1 (PRAD1: parathyroid adenomatosis 1) antibody, Cyl-1 antibody, D11S287E antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, G1/S-specific cyclin-D1 antibody, g1/S-specific cyclin-D1-like antibody, parathyroid adenomatosis 1 antibody, PRAD1 antibody, PRAD1 oncogene antibody, U21B31 antibody |
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| Cross Reactivity | Human, Rat |
| Applications | IP, WB |
| Immunogen | Cyclin D1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-Cyclin D1) as the immunogen |
Specifications
| Host | Mouse |
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| Clone | AF2G5 |
| Isotype | IgG1 kappa |
| Method of Purification | Cyclin D1 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000, IP: 2 ul |
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Storage & Safety
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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General Information
| Biological Significance | Cyclin D1 (Bcl-1 oncogene product), is a member of the Cyclin family that help control transition between phases of the cell cycle by acting as regulatory subunits of the Cdks. The D-type Cyclins are composed of three subtypes, Cyclin D1, D2 and D3. Cyclin D1 is essential for control of the cell cycle at the G1/S transitions and interacts with Cdk4 or Cdk6 protein kinases. On the recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Also Cyclin D1 involves in development and cancer. |
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