CYP11B2 protein (80-1570)
Purified Recombinant CYP11B2 protein (His tag)
Overview
Overview
| Synonyms | CYP11B2 antigen, LDOS protein, Aldosterone synthase protein, Aldosterone-synthesizing enzyme protein, C11B2 protein, CPN2 protein, CYP11B protein, CYP11B2 protein, CYP11BL protein, CYPXIB2 protein, Cytochrome P-450Aldo protein, Cytochrome P-450C18 protein, Cytochrome P450 11B2 protein mitochondrial, cytochrome P450 family 11 subfamily B, polypeptide 2 protein, cytochrome P450 subfamily XIB (steroid 11-beta-hydroxylase) protein, cytochrome P450 family 11, subfamily B polypeptide 2 protein, P-450C18 protein, P450aldo protein, P450C18 protein, steroid 11-beta-monooxygenase protein, steroid 11-beta/18-hydroxylase protein, Steroid 18-hydroxylase protein |
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| Species | Human |
| Protein Type | Recombinant |
Specifications
| Residues | 25-503 aa |
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| Expression System | Baculovirus |
| Tag/Conjugate | His tag |
General Information
| Biological Significance | CYP11B2 preferentially catalyzes the conversion of 11- deoxycorticosterone to aldosterone via corticosterone and 18- hydroxycorticosterone. Defects in CYP11B2 are the cause of corticosterone methyloxidase type 1 deficiency (CMO-1 deficiency); also known as aldosterone deficiency due to defect in 18- hydroxylase or aldosterone deficiency I. |
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