Cystatin C protein (30-1838)
Partially pure native Human Cystatin C protein
Overview
Overview
| Synonyms | CysC protein, Native Cystatin C antigen, Human Cystatin C protein, Cys C protein, CST3 protein, Cystatin-C, Cystatin-3, Neuroendocrine basic polypeptide, Post gamma globulin protein |
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| Species | Human |
| Protein Type | Native |
Specifications
| Source | Human Urine |
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| Grade & Purity | 10-50% pure |
| Form & Buffer | Supplied in liquid 10 mM Tris (pH 8.5), containing 20% Glycerol, 10 mM Benzamidine, and 0.09% Sodium Azide. |
| Concentration | 1-2 mg/ml |
Storage & Safety
| Storage | Store at 2-8 deg C. |
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| Contaminants | Bioburden count of < 10 CFU/ml |
| Biohazard Information | Tested negative for presence of HBsAg, Anti-HCV, Anti-HIV1/2 and DNA/RNA of HBV, HCV, and HIV1. |
General Information
| Biological Significance | Cystatin Cis aninhibitor of cysteine proteinases. It serves asan important physiological local regulator of enzyme activity. Cystatin C is mainly used as a biomarker of kidney function and through prediction of preclinicalkidney dysfunction, maypredict the risk of developing chronic kidney disease. Ithas also been implicated to play arole in brain disorders, such as Alzheimer's disease througha hereditary generalized amyloidosis due to Cystatin C amyloid deposition. Recently, it has been studied for its role in predicting new-onset cardiovascular disease. |
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