Cystatin C protein (80R-4365)

Purified Recombinant Cystatin C protein (His tagged)

Synonyms CST3 protein, CysC protein
Species Mouse
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using Cystatin C protein (His tag) (80R-4365)

Specifications

Residues 21-140 aa: ATPKQGPRML GAPEEADANE EGVRRALDFA VSEYNKGSND AYHSRAIQVV RARKQLVAGV NYFLDVEMGR TTCTKSQTNL TDCPFHDQPH LMRKALCSFQ IYSVPWKGTH SLTKFSCKNA HHHHHH
Expression System Insect cells
Grade & Purity > 95% pure
Molecular Weight 14.2 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeated freezing and thawing cycles.
Endotoxin Levels < 1.0 EU per 1 microgram of protein (determined by LAL method)

General Information

Biological Significance CST3, also known as Cystatin-C is a member of family 2 of the cystatin superfamily. This protein is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S. It indicates that a murine model should be relevant for studies of the human disease, hereditary Cystatin C amyloid angiopathy.

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Images

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SDS-PAGE analysis using Cystatin C protein (His tag) (80R-4365)



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Availability: In stock

Price: €300.20
Size: 50 ug
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