Cytochrome c antibody (20R-1430)
Rabbit polyclonal Cytochrome c antibody
Overview
Overview
| Synonyms | Polyclonal Cytochrome c antibody, Anti-Cytochrome c antibody, Cytochrome-c antibody, Cytochrome complexantibody, cyt c antibody |
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| Specificity | The Cytochrome c antibody detects the 12.6 kDa Cytochrome c from human, mouse, and rat samples. |
| Cross Reactivity | Human, Mouse, Rat (Bovine, Chicken, Dog, Fruit Fly, Horse, Kangaroo, Monkey, Pig, Pigeon, Rabbit, Sheep, Snail, Tuna, Turkey, Yeast, Zebrafish) |
| Applications | IP, WB |
| Immunogen | Cytochrome c antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 70 of rat Cytochrome c as the immunogen. |
| Assay Information | Cytochrome C Blocking Peptide, catalog no. 33R-10440, is also available for use as a blocking control in assays to test for specificity of this Cytochrome c antibody |
Specifications
| Host | Rabbit |
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| Method of Purification | Cytochrome c antibody was purified by affinity purification. |
| Form & Buffer | Supplied in PBS buffer, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Concentration | 200 ug/ml |
Usage & Assay Information
| Usage Recommendations | IP: 10-20 ug/ml, WB: 0.5-4 ug/ml |
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Storage & Safety
| Storage | Store at -20 deg C. For long-term storage, aliquot and freeze at -70 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Cytochrome c (MW 12,500) is an electron transport protein from mitochondria. It is released from mitochondria to cytoplasm during the early stages of apoptosis, prior to caspase activation, DNA fragmentation, and loss of membrane potential. The cytoplasmic Cytochrome c is associated with Apaf 1 and Caspase 9 to activate Caspase 3 and other caspases. |
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