D-dimer antibody (10-7900)
Mouse monoclonal D-dimer antibody
Overview
Overview
| Synonyms | Monoclonal D-dimer antibody, Anti-D dimer reductase antibody |
|---|---|
| Applications | ELISA, Immunoassays, Latex Immunoturbidimetric Assay, WB |
| Immunogen | D-dimer antibody was raised in mouse using homogenized fibrin clot, D-dimer or high molecular weight fibrin degradation products as the immunogen. |
| Assay Information | 10-7900 can be used in a sandwich immunoassay as a conjugate antibody in conjunction with 10-D100A as the coating antibody |
Specifications
| Host | Mouse |
|---|---|
| Clone | M18612DD |
| Isotype | IgG2a |
| Method of Purification | D-dimer antibody was purified by Protein A chromatography. |
| Form & Buffer | Supplied in PBS, pH 7.4, 0.1 % sodium azide (NaN3) |
Storage & Safety
| Storage | Store at 4 Deg C |
|---|---|
| Biohazard Information | This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropria |
General Information
| Biological Significance | D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrinogen protein. D-dimer concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation. |
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D-dimer antibody
Mouse monoclonal D-dimer antibody