DBH antibody (70R-14964)
Sheep polyclonal DBH antibody
Overview
Overview
| Synonyms | Polyclonal DBH antibody, Anti-DBH antibody, Dopamine beta-Hydroxylase antibody |
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| Applications | WB |
Images
Western Blot analysis using DBH antibody (70R-14964)
Western blot of human adrenal medulla lysate showing specific immunolabeling of ~75k DBH protein
Specifications
| Host | Sheep |
|---|---|
| Method of Purification | DBH antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000 |
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General Information
| Biological Significance | Defects in DBH are the cause of dopamine beta-hydroxylase deficiency, also known as norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction. |
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