Store at 4 deg C for up to 1 month. For long term storage, aliquot and store at -20 to -80 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information
This product contains sodium azide which is hazardous
General Information
Biological Significance
Delangin proteins facilitate enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation.