Desmocollin 3 antibody (10R-D103a)

Mouse monoclonal Desmocollin 3 antibody

Synonyms Monoclonal Desmocollin 3 antibody, Anti-Desmocollin 3 antibody
Specificity Human desmocollin 3
Cross Reactivity To be determined by end-user
Applications IHC-F, IHC-P, WB
Immunogen Desmocollin 3 antibody was raised in mouse using a synthetic peptide corresponding to a sequence present in the extracellular part of human desmocollin 3 as the immunogen.

Specifications

Host Mouse
Clone Dsc3-U114
Isotype IgG1
Grade & Purity Culture supernatant
Form & Buffer Cell culture supernatant with 0.09% NaN3.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Desmocollin-3 is a protein that in humans is encoded by the DSC3 gene. Desmocollin-3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The loss of these components leads to a lack of adhesion and a gain of cellular mobility.

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Availability: In stock

Price: €277.55
Size: 5 ml
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