Desmoglein 2 antibody (70R-12672)

Affinity purified Rabbit polyclonal Desmoglein 2 antibody

Synonyms Polyclonal Desmoglein 2 antibody, Anti-Desmoglein 2 antibody, Desmoglein 2, MGC117034 antibody, CDHF5 antibody, MGC117036 antibody, ARVD10 antibody, ARVC10 antibody, Desmoglein -2, Desmoglein -2 antibody, Desmoglein 2, Desmoglein 2 antibody, HDGC antibody, MGC117037 antibody, CMD1BB antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen Desmoglein 2 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 206 of Desmoglein 2

Images

Immunofluorescent staining using Desmoglein 2 antibody (70R-12672)

Immunofluorescence analysis of paraformaldehyde-fixed A431, using Desmoglein 2 antibody at 1:500 dilution.

Specifications

Host Rabbit
Isotype IgG
Method of Purification Desmoglein 2 antibody was purified by antigen-affinity chromatography
Molecular Weight 122 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

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Images

  • <div><font face=Calibri size=2>Immunofluorescent staining using Desmoglein 2 antibody (70R-12672)</font></div>     | Immunofluorescence analysis of paraformaldehyde-fixed A431, using Desmoglein 2 antibody at 1:500 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using Desmoglein 2 antibody (70R-12672)</font></div>     | Immunohistochemical staining of paraffin-embedded DU145 xenograft using Desmoglein 2 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using Desmoglein 2 antibody (70R-12672)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: 293T; B: H1299; C: Molt-4) using a 7.5 % SDS PAGE gel and Desmoglein 2 antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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