DGCR6 protein (His tag) (80R-2683)
Purified recombinant DGCR6 protein (His tag)
|Synonyms||Protein DGCR6 protein, DiGeorge syndrome critical region gene 6 protein, DGCR6, DGCR 6, DGCR-6, DGCR 6 protein, DGCR-6 protein|
SDS-PAGE analysis of DGCR6 protein (His tag) (80R-2683)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-220 aa: MGSSHHHHHH SSGLVPRGSH MGSMERYAGA LEEVADGARQ QERHYQLLSA LQSLVKELPS SFQQRLSYTT LSDLALALLD GTVFEIVQGL LEIQHLTEKS LYNQRLRLQN EHRVLRQALR QKHQEAQQAC RPHNLPVLQA AQQRELEAVE HRIREEQRAM DQKIVLELDR KVADQQSTLE KAGVAGFYVT TNPQELMLQM NLLELIRKLQ QRGCWAGKAA LGLGGPWQLP AAQCDQKGSP VPP|
|Grade & Purity||> 95% pure|
|Molecular Weight||27 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||DGCR6 shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This protein is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. Recombinant human DGCR6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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