DIAPH1 antibody (70R-12637)
Affinity purified Rabbit polyclonal DIAPH1 antibody
Overview
Overview
| Synonyms | Polyclonal DIAPH1 antibody, Anti-DIAPH1 antibody, DFNA1 antibody, DIAPH-1, DIAPH 1, DIAPH-1 antibody, diaphanous-related formin-1 antibody, FLJ25265 antibody, DRF1 antibody, hDIA1 antibody, DIAPH1 antibody, DIAPH1, DIAPH 1 antibody, protein diaphanous homolog 1 antibody, DIA1 antibody, LFHL1 antibody, diaphanous-related formin 1 antibody |
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| Cross Reactivity | Human |
| Applications | ICC, IF, IHC-P, WB |
| Immunogen | DIAPH1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 237 of DIAPH1 |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | DIAPH1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 141 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.69 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:1000, ICC:1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. |
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