Diazepam Binding Inhibitor antibody (20R-2924)
Rabbit polyclonal Diazepam Binding Inhibitor antibody
Overview
Overview
| Synonyms | Polyclonal Diazepam Binding Inhibitor antibody, Anti-Diazepam Binding Inhibitor antibody, DBI antibody, diazepam binding inhibitor (GABA receptor modulator antibody, acyl-CoA binding protein) antibody, ACBD1 antibody, Acbp antibody, Acoabp3 antibody, acyl-CoA binding protein antibody, acyl-CoA-binding protein antibody, acyl-Coenzyme A binding domain containing 1 antibody, acyl coenzyme A binding protein antibody, anon-WO0172774.131 antibody, BcDNA:RH39533 antibody, BOS_1891 antibody, CCK-RP antibody, CG8627-PA antibody, CG8627-PB antibody, cholecystokinin-releasing peptide antibody, trypsin-sensitive antibody, Dbi-PA antibody, Dbi-PB antibody, diazepam binding inhibitor antibody, diazepam-binding inhibitor antibody, diazepam binding inhibitor (dbi) antibody, Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein) antibody, Diazepam binding inhibitor (GABA receptor modulator antibody, acyl-Coenxyme A binding protein) antibody, diazepam binding inhibitor (GABA receptor modulator antibody, acyl-Coenzyme A binding protein) antibody, diazepam binding inhibitor antibody, splice form 1b antibody, diazepam-binding protein antibody, Dmel_CG8627 antibody, EGK_21463 antibody, endozepine antibody, Ep antibody, GABA receptor modulator antibody, LRRGT00046 antibody, octadecaneuropeptide antibody, Odn antibody, RNACOABP3 antibody, triakontatetraneuropeptide antibody, Ttn antibody, TTpA006p08.1 antibody |
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| Cross Reactivity | Human |
| Applications | IP, WB |
| Immunogen | Diazepam Binding Inhibitor antibody was raised in Rabbit using a recombinant human GST-fusion protein purified from E.coli as the immunogen |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000, IP: 1 ul |
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Storage & Safety
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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General Information
| Biological Significance | Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease. |
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