DNA polymerase gamma antibody (70R-12532)

Affinity purified Rabbit polyclonal DNA polymerase gamma antibody

Synonyms Polyclonal DNA polymerase gamma antibody, Anti-DNA polymerase gamma antibody, PolG-alpha antibody, FLJ27114 antibody, MIRAS antibody, MTDPS4A antibody, PEO antibody, POLG1 antibody, SANDO antibody, MTDPS4B antibody, MDP1 antibody, mitochondrial DNA polymerase catalytic subunit antibody, PolG catalytic subunit antibody, POLG antibody, POLGA antibody, SCAE antibody, DNA polymerase subunit gamma-1 antibody
Cross Reactivity Human
Applications ICC, IF, IHC-P, WB
Immunogen DNA polymerase gamma antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 779 and 1231 of DNA polymerase gamma

Images

Western blot analysis using DNA polymerase gamma antibody (70R-12532)

Western blot analysis of A. 50 ug Rat testis lysate/extract using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000

Specifications

Host Rabbit
Isotype IgG
Method of Purification DNA polymerase gamma antibody was purified by antigen-affinity chromatography
Molecular Weight 140 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.67 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:1000-1:10000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).

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Images

  • <div><font face=Calibri size=2>Western blot analysis using DNA polymerase gamma antibody (70R-12532)</font></div>     | Western blot analysis of A. 50 ug Rat testis lysate/extract using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Western blot analysis using DNA polymerase gamma antibody (70R-12532)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: MCF-7) using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000
  • <div><font face=Calibri size=2>Immunofluorescent staining using DNA polymerase gamma antibody (70R-12532)</font></div>     | Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1:200 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using DNA polymerase gamma antibody (70R-12532)</font></div>     | Immunohistochemical staining of paraffin-embedded Skeletal Muscle using DNA polymerase gamma antibody

Availability: In stock

Price: €395.09
Size: 100 ul
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