DNAJB2 protein (His tag) (80R-1549)
Purified recombinant Human DNAJB2 protein
|Synonyms||DnaJ homolog subfamily B member 2 protein, DNAJB 2 protein, DNAJB 2, DNAJB2, HSJ1 protein, DNAJB-2, HSPF3, DNAJB-2 protein|
Coomassie Blue stained SDS-PAGE of DNAJB2 protein (His tag) (80R-1549)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-277 amino acids: MGSSHHHHHH SSGLVPRGSH MGSMASYYEI LDVPRSASAD DIKKAYRRKA LQWHPDKNPD NKEFAEKKFK EVAEAYEVLS DKHKREIYDR YGREGLTGTG TGPSRAEAGS GGPGFTFTFR SPEEVFREFF GSGDPFAELF DDLGPFSELQ NRGSRHSGPF FTFSSSFPGH SDFSSSSFSF SPGAGAFRSV STSTTFVQGR RITTRRIMEN GQERVEVEED GQLKSVTING VPDDLALGLE LSRREQQPSV TSRSGGTQVQ QTPASCPLDS DLSEDEDLQL AMAYSLSEME AAGKKPADVF|
|Grade & Purity||> 90% pure|
|Molecular Weight||33 kDa (300aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 2mM DTT and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||DnaJB2, also known as HSJ1 or HSPF3, belongs to the DnaJ family. It is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The DnaJ proteins play a critical role in the HSP70 chaperone machine by interacting with HSP70 to stimulate ATP hydrolysis. DnaJB2 is important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. Recombinant human DNAJB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product