DNM1 antibody (Ser774) (70R-14968)
Sheep polyclonal DNM1 antibody (Ser774)
Overview
Overview
| Synonyms | Polyclonal DNM1 antibody, Anti-DNM1 antibody, DNM 1 antibody, DNM-1 antibody, DNM1, Dynamin 1 antibody, DNM antibody, Dynamin antibody |
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| Applications | IF, IHC, WB |
Images
Western Blot analysis using DNM1 antibody (Ser774) (70R-14968)
Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of ~95k dynamin phosphorylated at Ser774 (Control)
Specifications
| Host | Sheep |
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| Method of Purification | DNM1 antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000, IF: 1:1000, IHC: 1:1000 |
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General Information
| Biological Significance | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. |
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