DPC4 antibody (10R-7899)

Mouse monoclonal DPC4 antibody

Synonyms Monoclonal DPC4 antibody, Anti-DPC4 antibody, DPC4, DPC-4, DPC 4, DPC-4 antibody, DPC 4 antibody, SMAD4 antibody
Applications ICC, WB
Immunogen DPC4 antibody was raised in mouse using recombinant human Smad4 (DPC4) as the immunogen

Images

Western blot analysis using DPC4 antibody (10R-7899)

Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate

Specifications

Host Mouse
Clone IMD-89
Isotype IgG1
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.

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Images

  • Western blot analysis using DPC4 antibody (10R-7899) | Lane 1: Rat Brain Tissue Lysate, Lane 2: Rat Brain Tissue Lysate

Availability: In stock

Price: €220.86
Size: 100 ug
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