DR5 antibody (10R-6673)

Mouse monoclonal DR5 antibody

Synonyms Monoclonal DR5 antibody, Anti-DR5 antibody, DR-5 antibody, DR-5, DR5, DR 5 antibody, TRAILR2 antibody, TRAIL-R2 antibody, DR 5
Specificity Human
Applications Functional Assay
Assay Information This recombinant human HGF has been tested in a bioassay of dose-dependent stimulation of 4MBr5 cell proliferation. The ED50 for this is typically 50 ng/ml, corresponding to a specific activity of 2.0 x104 U/mg.

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Specifications

Host Mouse
Clone DJR2-2
Isotype IgG1 kappa
Method of Purification DR5 antibody was purified by affinity chromatography.
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The DJR2-2 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells.

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Availability: In stock

Price From: Price: €122.70

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Price From: Price: €122.70
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