DR5 antibody (10R-6673)
Mouse monoclonal DR5 antibody
Overview
Overview
| Synonyms | Monoclonal DR5 antibody, Anti-DR5 antibody, DR-5 antibody, DR-5, DR5, DR 5 antibody, TRAILR2 antibody, TRAIL-R2 antibody, DR 5 |
|---|---|
| Specificity | Human |
| Applications | Functional Assay |
| Assay Information | This recombinant human HGF has been tested in a bioassay of dose-dependent stimulation of 4MBr5 cell proliferation. The ED50 for this is typically 50 ng/ml, corresponding to a specific activity of 2.0 x104 U/mg. |
Specifications
| Host | Mouse |
|---|---|
| Clone | DJR2-2 |
| Isotype | IgG1 kappa |
| Method of Purification | DR5 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
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General Information
| Biological Significance | The DJR2-2 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells. |
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