EBNA2 antibody (10R-11308)
Rat Monoclonal EBNA2 antibody
Overview
Overview
| Synonyms | Monoclonal EBNA2 antibody, Anti-EBNA2 antibody, EBV-NA2 antibody, EBNA 2 antibody, Epstein Barr Virus Nuclear Antigen 2 antibody, EBNA-2 antibody |
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| Cross Reactivity | Human |
| Applications | IHC, IP, WB |
| Immunogen | EBNA2 antibodywas raised in Rat using a GST-tagged recombinant protein corresponding to human EBNA2 as the immunogen |
Specifications
| Host | Rat |
|---|---|
| Clone | M83171 |
| Isotype | IgG2a kappa |
| Method of Purification | EBNA2 antibody was purified using Protein G chromotography |
| Form & Buffer | Supplied in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide |
Storage & Safety
| Storage | Stable for 1 year at 2-8 deg C from date of receipt. |
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General Information
| Biological Significance | Epstein-Barr virus (EBV) is one of the eight known human herpes viruses and belongs to the Gammaherpes viriniae, the same subfamily as human herpesvirus type 8 (HHV-8). Herpes viruses have large double strand DNA genomes and are complex viruses often encoding over 35 proteins including enzymes involved in nucleic acid metabolism, DNA synthesis and protein processing in addition to viral structural proteins. These viruses are capable of entering a latent phase where the host shows no visible signs of infection and levels of infectious agent become very low. Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) is an EBV-encoded nuclear protein of 82 kDa. EBNA2 is essential for growth transformation of B-lymphocytes and has been shown to modulate the activity of several viral and cellular promoters. |
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