Ebola Virus VP40 protein (30-1837)
Recombinant Ebola Virus VP40 Matrix protein
Overview
Overview
| Synonyms | Recombinant Ebola Virus VP40 protein, Ebola Virus VP40 Matrix protein, Ebola VP40 protein, Ebola Zaire protein |
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| Species | Viral |
| Protein Type | Recombinant |
| Applications | ELISA, Lateral Flow, SDS-PAGE, WB |
| Assay Information | This Ebola VP40 matrix protein is highly reactive with the VP40 antibody pair, 10-2351 and 10-2352 and all three components are excellent reagents for optimizing immunoassays for Ebola virus. |
Images
Specifications
| Residues | 1-326 aa of Ebola VP40 protein with N-terminal Hexahistidine and GST tags. Zaire strain, Accession No. AHX24648 |
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| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Method of Purification | Purified using proprietary chromatographic techniques |
| Molecular Weight | 68 kDa |
| Tag/Conjugate | His-GST tag |
| Form & Buffer | Suppliedas liquid in 50mM Tris pH 8.5, 150mM NaCl with 10% glycerol, 2mM DTT and 1mM EDTA |
Usage & Assay Information
| Usage Recommendations | To be optimized by the end user |
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Storage & Safety
| Storage | Ships on dry ice. Upon receipt, aliquot and store at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | The Ebola VP40 protein is a viral matrix protein. VP40 coordinates numerous functions in the viral life cycle of the Ebola virus such as,regulation of viral transcription, morphogenesis,andpackaging and budding of mature virions. The VP40 monomer consists of two protein domains, the N-terminal oligomerization domain and the C-terminal membrane-binding domain, connected by a flexible linker. Study of the matrix protein VP40 is important due to the high mortality rate of the Ebola virus, which is listed as a WHO Risk Group 4 Pathogen, an HHS Select Agent, an NIH/NIAID Category A Priority Pathogen, a CDC Category A Bioterrorism Agent, and a Biological Agent for Export Control by the Australia Group |
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| Database Links | http://www.ncbi.nlm.nih.gov/protein/AHX24648 |
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