Endostatin protein (30R-2713)
Purified recombinant Human Endostatin protein
Overview
Overview
| Synonyms | Collagen alpha-1 XVIII chain protein |
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| Species | Human |
| Protein Type | Recombinant |
Specifications
| Expression System | Pichia pastoris |
|---|---|
| Grade & Purity | > 98% pure |
| Method of Purification | Endostatin protein was purified using a a proprietary chromatographic technique. |
| Molecular Weight | 20 kDa |
| Form & Buffer | Supplied as a sterile filtered liquid |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
|---|---|
| Endotoxin Levels | <0.1 ng/ug |
General Information
| Biological Significance | Endostatin has been identified as a C-terminal fragment of Collagen type 18, a recently identified member of a family of collagen-like proteins referred to as multiplexin family Endostatin specifically inhibits proliferation of endothelial cells although it does not affect the proliferation of EOMA cells. Endostatin also potently inhibits angiogenesis and tumor growth. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls and basement membranes. |
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