Eotaxin 2 protein (Mouse) (30R-AE021)
Purified recombinant Mouse Eotaxin 2 protein
Overview
Overview
| Synonyms | Eotaxin-2 protein, MPIF-2 protein, CCL24 protein, CkB-6 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of Eotaxin 2 protein corresponding to amino acids VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 10.3 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract Mouse lymphoytes using a concentration range of 10-100 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug(1 EU/ug). |
General Information
| Biological Significance | Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the Mouse homolog, without C-terminal truncation). |
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