EP300 antibody (10R-2005)

Mouse monoclonal EP300 antibody

Synonyms Monoclonal EP300 antibody, Anti-EP300 antibody, EP 300 antibody, EP-300, p300 antibody, EP 300, E1A binding protein p300 antibody, EP-300 antibody, EP300
Cross Reactivity Human
Applications ELISA, WB
Immunogen EP300 antibody was raised in Mouse using a purified recombinant fragment of EP300 expressed in E. coli as the immunogen.

Images

Western Blot analysis using EP300 antibody (10R-2005)

Western Blot showing EP300 antibody used against truncated EP300-His recombinant protein (1).

Specifications

Host Mouse
Clone 7D8A6
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein), and like CBP can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

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Images

  • Western Blot analysis using EP300 antibody (10R-2005) | Western Blot showing EP300 antibody used against truncated EP300-His recombinant protein (1).

Availability: In stock

Price: €285.10
Size: 100 ul
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