EPOr antibody was raised in sheep using partial cDNA of the extracellular domain of human EpoR expressed as a GST fusion protein in E. Coli as the immunogen.
Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles.
General Information
Biological Significance
The human erythropoietin receptor (EpoR) is located on stem and mature cells of the hematopoietic system. When activated by its native ligand, erythropoietin (Epo), EpoR mediates proliferation and maturation of the erythroid precursor cells leading to expansion of red cell populations.