ErbB-2 + HER-2 + Neu antibody (20R-CR001)

Rabbit polyclonal ErbB-2 + HER-2 + Neu antibody

Synonyms Polyclonal ErbB-2 + HER-2 + Neu antibody, Anti-ErbB-2 + HER-2 + Neu antibody, ErbB-2 (HER-2/Neu) antibody, ERBB 2 antibody, ERBB-2 antibody, ERBB 2, ERBB2, ERBB-2
Specificity Human
Cross Reactivity Monkey, mouse, rat
Applications IHC-F, IHC-P, IP, WB
Immunogen ErbB-2/HER-2/Neu antibody was raised in rabbit using a synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein as the immunogen.

Specifications

Host Rabbit
Method of Purification ErbB-2 + HER-2 + Neu antibody was purified by Protein A chromatography.
Molecular Weight 185 kDa (predicted detection band MW)
Form & Buffer Purified IgG supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration ~1.0 mg/ml

Usage & Assay Information

Usage Recommendations IHC-F: 2.5-5.0 ug/ml, IHC-P: 2.5-5.0 ug/ml IP: 10 ug/mg protein lysate, WB: 5-10 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein.

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Availability: In stock

Price From: Price: €432.72
Price From: Price: €432.72
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