This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
General Information
Biological Significance
c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and
ovarian tumors were found to overexpress the protein.