ErbB2 antibody (20R-1724)
Rabbit polyclonal ErbB2 antibody
Overview
Overview
| Synonyms | Polyclonal ErbB2 antibody, Anti-ErbB2 antibody, HER2-ErbB2 antibody, ErbB 2 antibody, c erb B2 antibody, v erb b2 antibody, her2 antibody, HER 2 antibody, Neu antibody, NGL antibody, TKR1 antibody, ErbB2, ErbB 2,ErbB-2,ErbB 2 antibody, ErbB-2 antibody |
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| Cross Reactivity | Human, Mouse |
| Applications | IP, WB |
| Immunogen | ErbB2 antibody was raised in Rabbit using synthetic peptide of human ErbB2 as the immunogen. |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Form & Buffer | Supplied in PBS buffer containing 30% glycerol, 1% BSA and 0.02% thimerosal. |
Usage & Assay Information
| Usage Recommendations | WB: 1:1000-1:2500 |
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Storage & Safety
| Storage | Store at -20 deg C. For long-term storage, aliquot and freeze at -70 deg C. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |
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