ERBB2 antibody (70R-17127)
Rabbit polyclonal ERBB2 antibody
Overview
Overview
| Synonyms | Polyclonal ERBB2 antibody, Anti-ERBB2 antibody, V Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 2 Neuro/Glioblastoma Derived Oncogene Homolog antibody, Erbb2 antibody, CD340 antibody, Her 2 antibody, Her 2/Neu antibody, Her2 antibody, Neu antibody, Ngl antibody, Tkr1Human Epidermal Growth Factor Receptor 2 antibody |
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| Cross Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Immunogen | ERBB2 antibody was raised in Rabbit using Human ERBB2 as the immunogen |
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | ERBB2 antibody was purified by Antigen Affinity chromatography |
| Form & Buffer | Supplied in PBS buffer with 0.02% Sodium Azide and 50% Glycerol, pH 7.3 |
Storage & Safety
| Storage | Store at 4 deg C for short term storage and -20 deg C for long term storage. Avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | ERBB2 is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |
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