ErbB2 antibody (Thr686) (70R-33578)
Rabbit polyclonal ErbB2 antibody (Thr686)
Overview
Overview
| Synonyms | Polyclonal ErbB2 antibody, Anti-ErbB2 antibody, ERBB2 antibody, V Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 2 Neuro/Glioblastoma Derived Oncogene Homolog antibody, HER2 antibody, CD340 antibody, Her 2 antibody, Her 2/Neu antibody, Her2 antibody, Neu antibody, Ngl antibody, Tkr1Human Epidermal Growth Factor Receptor 2 antibody |
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| Specificity | ErbB2 antibody detects endogenous levels of ErbB2 only when phosphorylated at threonine 686 |
| Cross Reactivity | Mouse, Rat |
| Applications | ELISA, IF |
| Immunogen | ErbB2 antibody was raised in Rabbit using a synthetic phosphopeptide derived from human ErbB2 around the phosphorylation site of threonine 686 (K-Y-TP-M-R) as the immunogen |
Images
Immunofluorescent staining using ErbB2 antibody (Thr686) (70R-33578)
Immunofluorescence analysis of HuvEc cells, using ErbB2 (Phospho-Thr686) antibody.
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Residues | Human: Thr686, Mouse: Thr736, Rat: Thr688 |
| Form & Buffer | Supplied in PBS buffer (without Mg2+and Ca2+), pH 7.4, 150mM NaCl with 0.02% sodium azide and 50% glycerol |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF: 1:100-1:500, ELISA: 1:5000 |
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Storage & Safety
| Storage | Store at -20 deg C for 1 year, store at 2-8 deg C for up to 1 month |
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General Information
| Biological Significance | ErbB2 is a protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. |
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