ESE1 antibody (70R-12507)

Affinity purified Rabbit polyclonal ESE1 antibody

Synonyms Polyclonal ESE1 antibody, Anti-ESE1 antibody, ESE-1 antibody, ERT antibody, E74-like factor 3 (ets domain transcription factor) antibody, ESE-1, ets domain transcription factor serine box (epithelial-specific) antibody, ELF3 antibody, ESE 1 antibody, epithelium-restricted Ets protein ESX antibody, E74-like factor 3 (ETS domain transcription factor serine box epithelial-specific) antibody, EPR-1 antibody, ETS-related transcription factor Elf-3 antibody, ESE-1 antibody, ESX antibody, epithelial-restricted with serine box antibody, ESE 1, ESE1, epithelium-specific Ets transcription factor 1 antibody
Cross Reactivity Human
Applications ICC, IF, IHC-P, WB
Immunogen ESE1 antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 309 and 371 of ESE1

Images

Immunofluorescent staining using ESE1 antibody (70R-12507)

Immunofluorescence analysis of methanol-fixed HeLa, using ESE1 antibody at 1:500 dilution.

Specifications

Host Rabbit
Isotype IgG
Method of Purification ESE1 antibody was purified by antigen-affinity chromatography
Molecular Weight 41 kDa
Form & Buffer Supplied as a concentrated soloution containing 1X PBS, 1% BSA, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations IF:1:100-1:500, ICC:1:100-1:500, IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.

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Images

  • <div><font face=Calibri size=2>Immunofluorescent staining using ESE1 antibody (70R-12507)</font></div>     | Immunofluorescence analysis of methanol-fixed HeLa, using ESE1 antibody at 1:500 dilution.
  • <div><font face=Calibri size=2>Immunohistochemical staining using ESE1 antibody (70R-12507)</font></div>     | Immunohistochemical staining of paraffin-embedded NCI-N87 xenograft using ESE1 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using ESE1 antibody (70R-12507)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: A431) using a 10 % SDS PAGE gel and ESE1 antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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