Estrogen Receptor antibody (10R-E117a)

Mouse monoclonal Estrogen Receptor antibody

Synonyms Monoclonal Estrogen Receptor antibody, Anti-Estrogen Receptor antibody, NR3A1 antibody, ER antibody, DKFZp686N23123 antibody, ESR-1 antibody, Era antibody, ESR antibody, ESR 1 antibody, ESRA antibody, ESR1, ESR 1, ESR1 antibody, ESR-1
Cross Reactivity Cow, human, mouse, rabbit, rat
Applications Affinity Purification, Gel Shift, IP
Immunogen Estrogen receptor antibody was raised in mouse using purified SDS-denatured calf uterus estrogen receptor as the immunogen.

Specifications

Host Mouse
Clone AER314
Isotype IgG1 gamma
Method of Purification Estrogen Receptor antibody was purified by Protein A chromatography.
Molecular Weight 67 kDa (predicted detection band MW)
Form & Buffer Antibody purified from Ascites fluid by Protein G Chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations Gel Shift: 1 mg/ml, IP: 2 ug/mg

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

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Availability: In stock

Price: €371.64
Size: 100 ug
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