Exodus 2 Protein (30R-AE011S)
Purified recombinant Human Exodus 2 protein
Overview
Overview
| Synonyms | CCL21 protein, 6Ckine protein, Exodus 2, Exodus-2 protein, Exodus 2, Exodus-2 protein, SLC protein, Exodus 2 protein, Exodus-2 |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Clone | M88089 |
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| Residues | Region of Exodus 2 protein corresponding to amino acids; SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P |
| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 12.2 kDa |
| Form & Buffer | Sterile filtered through a 0.2 micron filter. Lyophilized with no additives. Centrifuge vial prior to opening. Reconstitute in water to 0.1-1.0 mg/ml. Do not vortex. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | < 0.1 ng/μg of protein (< 1 EU/μg). |
General Information
| Biological Significance | Exodus-2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymph nodes of certainendothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines.--Recombinant Human Exodus-2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues. |
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