Exodus 2 protein (Mouse) (30R-AE024)
Purified recombinant Mouse Exodus 2 protein
Overview
Overview
| Synonyms | SLC protein, Exodus 2, Exodus-2 protein, 6Ckine protein, Exodus-2 protein, Exodus 2, Exodus 2 protein, Exodus-2, CCL21 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of Exodus 2 protein corresponding to amino acids SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 12 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract total human activated T cells cultured in the presence of IL2using a concentration range of 10 -100 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. |
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