FABP2 protein (His tag) (80R-1139)

Purified recombinant Human FABP2 protein

Synonyms Intestinal fatty acid binding protein 2 protein, MGC133132 protein, FABP2 protein, Intestinal fatty acid binding protein 2 FABP 2 protein, FABP-2 protein, Intestinal fatty acid binding protein 2 protein, I-FABP protein, Fatty Acid Binding Protein-2, Fatty acid binding protein 2 intestinal protein, I FABP protein, Fatty acid binding protein protein, Fatty acid binding protein intestinal protein, FABP 2, FABP-2, FABPI protein, FABP 2 protein, FABP2, IFABP protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of FABP2 protein (His tag) (80R-1139)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-132 amino acids: MGSSHHHHHH SSGLVPRGSH MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSAFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 17.3 kDa (152 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance FABP2, also known as intestinal fatty acid binding protein 2 (I-FABP), is expressed in the epithelium of the small intestine by mature enterocytes. FABP2 is thought to facilitate of cellular uptake and transport of long-chain fatty acids within enterocytes and may also help maintain energy homeostasis by functioning as a lipid sensor. This protein binds saturated long-chain fatty acid with a high affinity, but binds with a low affinity to unsaturated long-chain fatty acid. The Ala to Thr substitution at residue 54 of FABP2 is associated with higher total cholesterol, with stroke incidence, elevation of fasting and postprandial triglyceride, insulin resistance, and higher nonesterified fatty acid (NEFA) concentrations. Recombinant human FABP2, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of FABP2 protein (His tag) (80R-1139) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €216.40
Size: 100 ug
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