Factor VII antibody (70R-12565)

Affinity purified Rabbit polyclonal Factor VII antibody

Synonyms Polyclonal Factor VII antibody, Anti-Factor VII antibody, coagulation factor VII antibody, eptacog alfa antibody, FVII coagulation protein antibody, serum prothrombin conversion accelerator antibody, F7 antibody, proconvertin antibody, SPCA antibody
Cross Reactivity Human, Mouse
Applications IHC-P, WB
Immunogen Factor VII antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 209 and 466 of Factor VII

Images

Western blot analysis using Factor VII antibody (70R-12565)

Western blot analysis of 30 µg of whole cell lysate (A:H1299) using a 7.5 % SDS PAGE gel and Factor VII antibody at a dilution of 1:500

Specifications

Host Rabbit
Isotype IgG
Method of Purification Factor VII antibody was purified by antigen-affinity chromatography
Molecular Weight 52 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.74 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.

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Images

  • <div><font face=Calibri size=2>Western blot analysis using Factor VII antibody (70R-12565)</font></div>     | Western blot analysis of 30 µg of whole cell lysate (A:H1299) using a 7.5 % SDS PAGE gel and Factor VII antibody at a dilution of 1:500
  • <div><font face=Calibri size=2>Immunohistochemical staining using Factor VII antibody (70R-12565)</font></div>     | Immunohistochemical staining of paraffin-embedded normal gastric epithelium (gland) using Factor VII antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using Factor VII antibody (70R-12565)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A:NIH-3T3) using a 10 % SDS PAGE gel and Factor VII antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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