Factor VII protein (30C-CP2052U)

Purified native Human Factor VII protein

Synonyms Complement Factor VII
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human serum/plasma
Grade & Purity > 95% pure
Molecular Weight 50 kDa
Form & Buffer 50% Glycerol/H2O (vol/vol).
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Bioactivity 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa.

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Availability: In stock

Price: €277.55
Size: 20 ug
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