Factor VIII antibody (70R-10621)

Affinity purified sheep polyclonal Factor VIII antibody

Synonyms Polyclonal Factor VIII antibody, Anti-Factor VIII antibody, Complement Factor VIII antibody
Specificity Human Factor VIII
Applications User optimized
Immunogen Factor VIII antibody was raised in sheep using human Factor VIII purified from concentrate as the immunogen.

Specifications

Host Sheep
Isotype IgG
Method of Purification Factor VIII antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50% (v/v) glycerol.

Storage & Safety

Storage Store at -10 to -20 deg C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.

General Information

Biological Significance Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder. Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa.

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Availability: In stock

Price: €478.53
Size: 500 ug
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