Factor VIII antibody (biotin) (60R-1060)
Sheep polyclonal Factor VIII antibody (biotin) conjugated
Overview
Overview
| Synonyms | Polyclonal Factor VIII antibody, Anti-Factor VIII antibody, Complement Factor VIII antibody |
|---|---|
| Specificity | Human Factor VIII |
| Applications | User optimized |
| Immunogen | Factor VIII antibody (biotin) was raised in sheep using human Factor VIII purified from concentrate as the immunogen. |
Specifications
| Host | Sheep |
|---|---|
| Isotype | IgG |
| Method of Purification | Factor VIII antibody (biotin) was purified by affinity chromatography. |
| Tag/Conjugate | Biotin |
| Form & Buffer | Supplied in liquid form in PBS containing 1 mg/ml bovine albumin and 0.1% sodium azide (w/v), pH 7.4. |
Storage & Safety
| Storage | Store at 2-8 deg C. |
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General Information
| Biological Significance | Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder. Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa. |
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