Factor XIII Subunit A antibody (70R-10616)
Affinity purified sheep polyclonal Factor XIII Subunit A antibody
Overview
Overview
| Synonyms | Polyclonal Factor XIII Subunit A antibody, Anti-Factor XIII Subunit A antibody, Fibrin Stabilizing Factor Subunit A antibody, Complement Factor XIII Subunit A antibody |
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| Specificity | Human Factor XIII Subunit A |
| Applications | User optimized |
| Immunogen | Factor XIII Subunit A antibody was raised in sheep using human Factor XIII Subunit A (A2) purified from plasma as the immunogen. |
Specifications
| Host | Sheep |
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| Isotype | IgG |
| Method of Purification | Factor XIII Subunit A antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in liquid form in 10 mM HEPES, pH 7.4, 150 mM NaCl, 50% (v/v) glycerol |
Storage & Safety
| Storage | Store at -10 to -20 deg C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. |
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General Information
| Biological Significance | Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic A subunits and two carrier B subunits. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa; its activation into Factor XIIIa requires calcium as a cofactor. |
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