Factor XIII Subunit A antibody (FITC) (60R-1066)
Sheep polyclonal Factor XIII Subunit A antibody (FITC) conjugated
Overview
Overview
| Synonyms | Polyclonal Factor XIII Subunit A antibody, Anti-Factor XIII Subunit A antibody, Fibrin Stabilizing Factor Subunit A antibody, Complement Factor XIII Subunit A antibody |
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| Specificity | Human Factor XIII Subunit A |
| Applications | User optimized |
| Immunogen | Factor XIII Subunit A antibody (FITC) was raised in sheep using human Factor XIII Subunit A (A2) purified from plasma as the immunogen. |
Specifications
| Host | Sheep |
|---|---|
| Isotype | IgG |
| Method of Purification | Factor XIII Subunit A antibody (FITC) was purified by affinity chromatography. |
| Tag/Conjugate | FITC |
| Form & Buffer | Phosphate-buffered saline containing 0.1 mg/ml bovine albumin and 0.1% sodium azide (w/v), pH 7.4. |
Storage & Safety
| Storage | Store at 2-8 deg C and protect from light. |
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General Information
| Biological Significance | Factor XIII is a transglutaminase that circulates in the plasma as a heterotetramer of two catalytic A subunits and two carrier B subunits. When thrombin has converted fibrinogen to fibrin, the latter forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa; its activation into Factor XIIIa requires calcium as a cofactor. |
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