FAN antibody (70R-12744)

Affinity purified Rabbit polyclonal FAN antibody

Synonyms Polyclonal FAN antibody, Anti-FAN antibody, factor associated with N-SMase activation antibody, factor associated with neutral sphingomyelinase activation antibody, NSMAF antibody, FAN antibody, protein FAN antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen FAN antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 262 and 570 of FAN

Images

Immunohistochemical staining using FAN antibody (70R-12744)

Immunohistochemical staining of paraffin-embedded T(gastric CA) using FAN antibody at a dilution of 1:100

Specifications

Host Rabbit
Isotype IgG
Method of Purification FAN antibody was purified by antigen-affinity chromatography
Molecular Weight 104 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.93 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:500, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation.

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using FAN antibody (70R-12744)</font></div>     | Immunohistochemical staining of paraffin-embedded T(gastric CA) using FAN antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using FAN antibody (70R-12744)</font></div>     | Western blot analysis of A: Non-transfected lysate; B: NSMAF transfected lysate using a 7.5 % SDS PAGE gel and FAN antibody at a dilution of 1:500

Availability: In stock

Price: €395.09
Size: 100 ul
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