FasL antibody (70R-FG002)

Affinity purified Goat polyclonal FasL antibody

Synonyms Polyclonal FasL antibody, Anti-FasL antibody, sFASL antibody, APTL antibody, TNFSF6 antibody, CD95L antibody, soluble Fas Ligand antibody, Apo I Ligand antibody
Specificity Human FasL
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen FasL antibody was raised in goat using highly pure recombinant human FasL/Apo1L as the immunogen.

Specifications

Host Goat
Molecular Weight 17.6 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.08-0.1 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Fas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: €185.94
Size: 50 ug
OR
Shipping
View Our Distributors