FGF18 protein (30R-AF007)

Purified recombinant Human FGF18 protein

Synonyms FGFI protein, FGF18, FGF 18 protein, FGF-18, FGF-18 protein, FGF 18, FGF-18 protein, Fibroblast Growth Factor-18 protein, zFGF5 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF18 protein corresponding to amino acids AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR.
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 20.1 kDa
Form & Buffer Lyophilized from 10mM Tris, pH 8.0, with 20mM NaCl. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is approximately 0.5 ng/ml, corresponding to a specific activity of approximately 2 x 10^6 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance FGF18 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF18 is an essential regulator of long bone and calvarial development. FGF18 signals through FGFR 1c, 2c, 3c, and 4.

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Availability: In stock

Price: €211.69
Size: 25 ug
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