FGF2 protein (30R-2100)
Purified recombinant Bovine fusion protein
Overview
Overview
| Synonyms | HBGF-2 protein, FGFB protein, BFGF protein, FGF 2 protein, fibroblast growth factor 2 protein, FGF 2, fibroblast growth factor 2, FGF2 protein, FGF-2, FGF2, FGF-2 protein |
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| Species | Bovine |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Expression System | E.coli |
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| Grade & Purity | > 95% pure |
| Method of Purification | FGF2 protein was purified by Heparin affinity chromatography |
| Molecular Weight | 18 kDa |
| Form & Buffer | Supplied in lyophilized form in 1 ml phosphate buffered saline (pH 6), supplemented with 5 mM glutathion |
Usage & Assay Information
| Bioactivity | < 1 ng/ml for half maximum stimulation of cell proliferation with bovine aortic endothelial cells (BAE cells) |
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Storage & Safety
| Storage | Store at 2-8 deg C in lyophilized form. Following reconstitution aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | In normal tissue, basic fibroblast growth factor is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. It stays membrane-bound as long as there is no signal peptide. It has been hypothesized that, during both wound healing of normal tissues and tumor development, the action of heparan sulfate-degrading enzymes activates bFGF, thus mediating the formation of new blood vessels, a process known as angiogenesis. |
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